Obeticholic acid (OCA) is a semi-synthetic bile acid analogue that acts as a potent and selective agonist of the farnesoid X receptor (FXR), a key nuclear bile acid receptor. By activating FXR, OCA induces the expression of fibroblast growth factor 19 (FGF-19), which plays a crucial role in regulating bile acid, glucose, and lipid metabolism. […]