Si et al. propose an innovative vaccine strategy that utilizes PROTAC technology to create artificially attenuated influenza strains, a strategy that promises to overcome the limitations of traditional vaccine preparation methods. By linking the proteasome-targeting domain (PTD) to a specific protein of the influenza virus, and using the host cell’s ubiquitin-proteasome system, they successfully degraded […]
siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation (Fig. 1). The mRNA is targeted for cleavage through the catalysis of the RISC protein Ago2, a member of the Argonaute family. In addition, other Ago proteins (Ago1, Ago3, and Ago4) […]
During protein synthesis and function, the N-terminal sequence not only determines the starting amino acid of the protein chain but often contains signal sequences that guide proper intracellular localization and processing. These N-terminal signal sequences play crucial roles in secretion, membrane protein insertion, and recombinant protein design. Comprehensive analysis and verification of N-terminal signal sequences […]
For anyone considering affiliate partnerships in 2025, two names stand out: Bet365 vs Dafabet. Both are trusted global platforms, but they cater to different markets and audiences, making the choice highly dependent on your traffic goals. Bet365 is a well-established global brand with a reputation for transparency, stability, and long-term growth. Its affiliate model offers […]
When it comes to creating professional embroidery, one of the most important steps is preparing your design in the right format. If you’re working with a Pfaff embroidery machine, you already know that it requires properly formatted stitch files for clean, flawless output. This is where Pfaff logo conversion comes in. Whether you’re embroidering a […]
Imagine slipping into bed after a long day and finding a perfectly smooth surface that doesn’t budge all night. That’s the charm of fitted bed sheets—a simple upgrade that makes life easier and more stylish. In India’s fast-changing home décor landscape, fitted bed sheets are becoming more than just a bedding essential. They’re part of a lifestyle—bringing comfort, […]
In today’s technology-driven job market, data science has transformed into one of the most influential and high-paying domains for professionals looking to redesign their careers. Companies across industries are relying heavily on data-driven insights, machine learning (ML), and artificial intelligence (AI) to make decisions and stay competitive. To prepare for this transformation, the Python Data Science Course […]
How to Avoid Hidden Pitfalls When Hiring a Digital Marketing Company in Mumbai Finding the right digital marketing company in Mumbai is a bit like finding a business partner—you need someone who understands your vision, communicates clearly, and delivers real results. Yet, many businesses walk into this decision blind, falling for fancy pitches, low prices, […]
The northern region of India includes the land of the maharajas (Rajasthan), home of the Taj Mahal (Agra), the city of the Ganges River (Varanasi), the ancient city of Delhi, and the Golden Temple (Punjab). Stretching across vibrant geographical dissimilarities, northern India exhibits a colorful fusion of various languages, cultural systems, climatic zones, cuisines, and […]
Looking for a trusted and hassle-free way to enjoy cricket online? Asia Play Online Cricket ID provides a smooth, secure, and quick solution for fans who want a verified account to explore live matches and digital platforms. With instant activation through WhatsApp, you can get started in just a few minutes without lengthy paperwork. What […]
